Update 8th April
Click on link below to view communication regarding MHRA and JCVI announcement regarding Oxford/AstraZeneca Vaccine and next steps
UPDATE 7th April
The Medicines and Healthcare products Regulatory Agency (MHRA) and the Government’s independent expert advisory body, the Commission on Human Medicines (CHM), is conducting a thorough review of reports of extremely rare thromboembolic events including cerebral venous sinus thrombosis (CVST) occurring in conjunction with thrombocytopaenia following the AstraZeneca COVID-19 vaccine. This notification informs you of the current status of the review and treatment guidance and provides information on how to report suspected cases.
By 31st March 2021, MHRA had received Yellow Card reports of 79 cases of thromboembolic events with concurrent thrombocytopaenia following vaccination with COVID-19 Vaccine AstraZeneca, 44 cases of cerebral venous sinus thrombosis (CVST) with thrombocytopaenia and 35 cases of other major thrombotic events, including one arterial, with thrombocytopaenia. These cases occurred in 51 women and 28 men, aged from 18 to 79 years. The estimated number of doses of vaccine administered in the UK by 31st March was 20.2 million giving an overall case incidence of 4.4 per million doses.
All reports are being followed up for clinical details and 19 cases have had a fatal outcome. Some cases have positive platelet factor 4 (PF4) antibodies and elevated D-dimer. In reports where this information was provided, all cases occurred after a first dose of the vaccine.
The CHM has carefully considered all available data, noting the need for further clinical details on the case reports and that data are also lacking on the background rate of CVST, including during the pandemic because Covid infection has been associated with thrombotic events. The CHM has advised that the currently available evidence does not establish a causal association between the AstraZeneca COVID-19 Vaccine and these events, but investigations (epidemiological and mechanistic) need to continue. The CHM’s advice remains that the overall benefits of the vaccines against COVID-19 continue to outweigh any risks in the vast majority of people, and that the evidence does not currently support excluding any age group from vaccination. In view of the available data, COVID-19 Vaccine AstraZeneca is contraindicated in patients with a history of major venous and arterial thrombosis with thrombocytopenia. COVID-19 Vaccine AstraZeneca should only be given to patients with a history of CVST, acquired or hereditary thrombophilia, heparin-induced thrombocytopenia, or antiphospholipid syndrome when the benefits outweigh any potential risks.
Because these events are extremely rare and a comparatively small number of second doses have been given, it is currently not known how frequently these events may occur following a second dose of the vaccine. As a precaution, anyone who experienced cerebral or other major blood clots occurring with low levels of platelets after their first vaccine dose of COVID-19 Vaccine AstraZeneca should not have their second dose.
Anyone who did not have these side effects should come forward for their second dose when invited.
COVID-19 vaccine advice in pregnancy remains that pregnant women should discuss with their healthcare professional whether the benefits of having the vaccine outweigh the risks for them, noting the extremely rare risk of thromboembolic events with concurrent thrombocytopaenia referred to above.
The MHRA recently confirmed that the evidence to date does not suggest that the COVID-19 Vaccine AstraZeneca causes venous thromboembolism without a low platelet count.
Further information is available from the British Society for Haematology guidance issued on thrombosis and thrombocytopaenia possibly occurring after vaccination with COVID-19 vaccines. This includes information on presentation and typical laboratory features, and treatment recommendations. The guidance also includes advice on recommended investigations for possible cases.
Advice for the public
While the MHRA continues to investigate these cases, as a precautionary measure anyone that develops symptoms after vaccination is advised to seek prompt medical advice, such as:
Furthermore anybody with new onset of severe or persistent headache that does not respond to simple painkillers starting four days or more after vaccination should speak to their doctor.
UPDATE 22nd March
We have now filled the last of our appointments for 1st vaccinations.
We apologise to anybody who has received a text this afternoon and been told there are no appointments left – there appears to be messages that are delayed in the system.
Thank you to everybody who has supported the vaccination programme with the surgery, we will contact those needing their 2nd vaccine as soon as we have appointments available.
Anybody who has received an invitation for a 1st vaccine, please call 119 or www.nhs.uk/covidvaccination
UPDATE 15th March
Safety of Oxford/AstraZeneca COVID-19 vaccine
The World Health Organisation and European Medicines Agency both say there is no indication of a link between the vaccine and reports of blood clots.
In a statement, Dr Phil Bryan, MHRA Vaccines Safety Lead, said: “Vaccine safety is of paramount importance and we continually monitor the safety of vaccines to ensure that the benefits outweigh any potential risks. It has not been confirmed that the report of a blood clot, in Denmark, was caused by the COVID-19 Vaccine AstraZeneca. The Danish, Norwegian and Icelandic authorities’ action to temporarily suspend use of the vaccine is precautionary whilst they investigate. Blood clots can occur naturally and are not uncommon.
“More than 11 million doses of the COVID-19 Vaccine AstraZeneca vaccine have now been administered across the UK. Reports of blood clots received so far are not greater than the number that would have occurred naturally in the vaccinated population. The safety of the public will always come first. We are keeping this issue under close review but available evidence does not confirm that the vaccine is the cause. People should still go and get their COVID-19 vaccine when asked to do so.”
A further statement from AstraZeneca provides additional detail including: “A careful review of all available safety data of more than 17 million people vaccinated in the European Union (EU) and UK with COVID-19 Vaccine AstraZeneca has shown no evidence of an increased risk of pulmonary embolism, deep vein thrombosis (DVT) or thrombocytopenia, in any defined age group, gender, batch or in any particular country.
“So far across the EU and UK, there have been 15 events of DVT and 22 events of pulmonary embolism reported among those given the vaccine, based on the number of cases the company has received as of 8 March. This is much lower than would be expected to occur naturally in a general population of this size and is similar across other licensed COVID-19 vaccines.”
UPDATE 8TH MARCH
Covid-19 Vaccination Update
On behalf of the Practice Partners, I write to advise that we will be contacting patients over the next few weeks to arrange their second Covid-19 vaccination. You do not need to contact the surgery, as we will contact you.
We are also expecting a limited supply of vaccines to provide a first dose for eligible patients, again we will contact you when supplies become available. If you are eligible and do not wish to wait for the Practice to contact you, please visit – http://nhs.uk/covidvaccination or ring 119. When booking your vaccine this will be provided at one of the mass vaccination sites / locations in the area.
We will publish updated information regarding our vaccination programme on our website and Facebook page when it becomes available
Please note that the surgery will not be providing vaccinations for the Government groups 7-9, as this will be undertaken at one of the mass vaccination sites / locations.
Dr Fiona Durnian
UPDATE 23rd February
The government has recently extended the cohort of people who are identified as extremely clinically vulnerable from Covid and are now required to shield. You may have recently received a letter informing you of this. It has come to our attention some patients have been identified incorrectly. We are reviewing the medical records of newly identified patients to check if the advice to shield is correct.
Should we find that you have been identified incorrectly we will contact you to advise of this change in status on your medical record.
In the interim, please continue to follow the advice on the Government letter you have received.
Frontline health and social care workers
If you are a frontline health and social care worker and have not yet been offered or received your first vaccine please contact us via this email address firstname.lastname@example.org and we will respond to your request as a priority.
Tuesday 9th February
People aged 70 and over who have not yet been vaccinated against Covid and who would like to be are today being asked to contact the NHS to arrange a jab.
Until now the NHS has asked people to wait until they are contacted to help ensure that those who are most vulnerable are protected first – and that remains the case for most people.
However, to ensure absolutely everyone is offered the vaccine, people aged 70 and over can now contact the NHS so they can be vaccinated by the middle of this month.
You can contact the surgery to book in for a vaccine or arrange a vaccination is through the national booking
Anyone unable to book online can call 119 free of charge, anytime between 7amand 11pm seven days a week. If a suitable and convenient slot is not available people can also call their GP practice.
Many who have not yet booked an appointment are already receiving follow up letters and phone calls this week to encourage them to take up the offer of a jab.
GP teams have also been asked to contact their clinically extremely vulnerable patients, who have been asked to shield, to ensure they have been offered the vaccine.
Anyone who received a letter in 2021 asking them to shield, should also receive an invitation from us as well as an invitation from the national booking service inviting them for a jab.
People in priority groups who are given a vaccination appointment by both their local GP team and the National Booking Service should cancel the one they do not want so the slot can be used by someone else.
Health and social care workers, who are also among the top four priority groups for vaccination, should speak to their employer about arranging their jab.
Thursday 4th February
As part of Northwich PCN we are now successfully vaccinating group 4, patients over 70 and clinically extremely vulnerable. We have had clinics running all week, the next clinic for Danebridge patients is on Sunday.
UPDATE Tuesday 26th January
Winsford Morrison’s covid vaccination site will be going live on Thursday this week (28th January 2021) and will have a weekly capacity of 5000 vaccinations.
Patients will be sent a letter by NHS England and given a unique reference number to use on the website or by phone. They are then offered a range of sites to access and timeslots from which they choose. The booking system also books a 2nd vaccination at the same site 12 weeks later to ensure both are booked in.
You can either book to go to Winsford, or wait to be invited by us to attend the Kingsmead Clinic
UPDATE Monday 25th January
Lots of people are contacting us to enquire about their covid vaccination. We understand that this is important and we are working as hard as we can to facilitate this monumental vaccination programme.
Danebridge’s next vaccination clinic is the 1st and 2nd of February and we will be contacting patients aged 75years
and older directly to invite them for this.
We will be expecting another delivery of vaccines shortly and will be able to update you further when we know more information about this.
Please do not ring the surgery to make enquiries about when your vaccination will be, this is only blocking the phone lines for patients ringing with urgent medical problems.
Thank you for your patience, support and understanding.
UPDATE THURSDAY 21st January
Our covid vaccination clinics are still runnning today and tomorrow, despite the floods and snow
UPDATE TUESDAY 12th January –
On Monday, January 11th 2021, the Etihad Tennis Club in Manchester also became one of the country’s first large-scale, regional vaccination sites.
Nationally, letters are being sent out to more than 600,000 people aged 80 and over who live up to a 45 minute drive from one of the new centres, inviting them to book an appointment.
The centres are an additional option for people, who can book an appointment at one of the seven centres through a national booking service either online or over the phone. If it is not convenient for them, they can instead be jabbed at one of their local vaccination centres in the coming weeks.
We would advise that patients should wait to be contacted by the practice but you do have the option to book online elsewhere if you don’t wish to wait.
UPDATE 4th January –
We are very pleased to announce that we will be starting to invite patients for the covid vaccination this week at Kingsmead Clinic. Our vaccinations will commence On Friday 8th January. If you are not contacted in the first batch please do not worry – we will be vaccinating the oldest members of our community first. You do not need to contact the surgery to book the appointment, you will be contacted by a member of our team.
The Northwich Primary Care Network (PCN) Vaccination Centre is Kingsmead Surgery, here are some things you need to be aware of:
Thank you for following this advice
Please help us to deliver the COVID-19 vaccination programme safely and effectively by following this simple guidance:
1. We will contact you when is the right time for you to come forward. Please do not contact the NHS to seek a vaccine before then.
2. When you are invited for a vaccine, please act on your invite and make sure you attend appointments when you arrange them.
3. Please continue to wear a face covering and follow social distancing and hand hygiene guidance as, until a vaccine has been fully rolled out, this is the most effective way to reduce transmission of the virus and help save lives